Saturday, September 12, 2026

Melatonin Use and Heart Health

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Introduction to Melatonin and Heart Health

The recent headlines linking melatonin to heart failure have sparked concern among those who use the sleep-related supplement. However, heart experts urge the public not to lose sleep over these reports. A preliminary study has raised questions about the safety of long-term use of melatonin for insomnia, but doctors emphasize that this kind of observational study cannot prove that melatonin use plays a role in heart disease.

Understanding Melatonin

Melatonin is a hormone that regulates our sleep cycles, and our bodies naturally produce it. Levels of melatonin normally increase as it gets darker in the evening, triggering drowsiness. People may take lab-produced melatonin to help them fall asleep or to adjust for jet lag or time changes.

The Study’s Findings

The new study used international electronic health records to track adults diagnosed with insomnia who had a melatonin prescription that suggested they used the supplement for at least a year. Over five years, 4.6% of the chronic melatonin users developed heart failure compared to 2.7% of insomnia patients whose charts showed no melatonin use. However, the study has not undergone peer review, and there are limitations to the research. For example, only certain countries require a melatonin prescription, and in the U.S., it’s available over-the-counter, meaning Americans in the study might have used the supplements without it being recorded.

Limitations of the Study

The study also did not show dosages, and U.S. supplements don’t require government approval, meaning brands can vary in their ingredients. The researchers characterized the findings as a call for more research. Patients wondering about melatonin should talk it over with their doctors, who generally recommend it for short-term use, like for jet lag.

Expert Opinions

Doctors have long known that too little or interrupted sleep raises the risk of heart disease. However, heart experts say that this kind of study can’t prove that melatonin use plays any role — instead of the insomnia patients were trying to treat. "We should not raise the alarm and tell patients to stop taking all their melatonin," said Dr. Pratik Sandesara, an interventional cardiologist at Emory Healthcare who wasn’t involved with the research.

The Importance of Sleep Hygiene

One key to better shut-eye is to practice better sleep hygiene, like making sure your room is dark. "When we expose ourselves to blue light in particular at night, we are diminishing our melatonin levels. That’s science," said Northwestern University cardiology chief Dr. Clyde Yancey. Sleep problems aren’t about "just being sleepy and tired — they’re putting yourself at risk."

Conclusion

In conclusion, while the study raises questions about the safety of long-term melatonin use, it’s essential to approach the findings with caution. Patients should talk to their doctors about melatonin use and practice good sleep hygiene to minimize the risk of sleep-related problems. The study’s findings should be seen as a call for more research, rather than a reason to stop taking melatonin altogether.

FAQs

  • Q: Is melatonin safe to use for insomnia?
    A: Melatonin is generally considered safe for short-term use, but long-term use may have unknown effects on heart health.
  • Q: Can melatonin cause heart failure?
    A: The study found a link between long-term melatonin use and heart failure, but it’s essential to note that the study has limitations and more research is needed to confirm the findings.
  • Q: How can I practice good sleep hygiene?
    A: Practicing good sleep hygiene includes making sure your room is dark, avoiding blue light at night, and establishing a consistent sleep schedule.
  • Q: Should I stop taking melatonin?
    A: Patients should talk to their doctors about melatonin use and follow their recommendations. It’s not necessary to stop taking melatonin altogether, but it’s essential to be aware of the potential risks and benefits.
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