Thursday, October 2, 2025

Botox has a new use — treating ‘no-burq syndrome’

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Burping: The Unspoken Issue That Can Affect Millions

The Condition

Burping is often considered a "faux pas," as it can be embarrassing and off-putting, especially in social situations. However, for some, the inability to burp can be an issue that can cause discomfort. There is even a medical name for the condition: retrograde cricopharyngeal dysfunction (R-CPD), also known as "no burp syndrome."

What Causes No Burp Syndrome?

The cricopharygeus is the main muscle of the upper esophageal sphincter, the top gate of the food pipe. With no burp syndrome, this muscle does not relax, which interferes with the burping process, according to Neil Chheda, MD, associate professor and vice chair in the department of otolaryngology and chief of the division of laryngology at UF Health in Gainesville, Florida.

Who Can Be Affected?

Both men and women can be affected, and risk factors for developing this condition are not known, Chheda said. It may not seem like an inability to burp is a big deal, but it can bring severe challenges, the doctor said.

The Impact on Daily Life

Those who can’t burp may report quality of life issues, such as bloating, a gurgling noise, and discomfort with certain foods and drinks, such as carbonated beverages, Chheda said. Priya Krishna, MD, an otolaryngologist in the department of head and neck surgery at Loma Linda University in California, agreed that no burp syndrome can cause "significant psychological distress" in the affected person.

A Potential Remedy: Botox

If over-the-counter options, prescription medications, and lifestyle tweaks don’t solve the burping issues, patients can turn to Botox for a potential remedy, medical experts say. Botox works by preventing a motor nerve from releasing the chemical transmitter that signals a muscle to contract. When Botox is injected into the cricopharygeus, the muscle can’t contract, and thereby relaxes and permits the venting of the esophagus, according to Dr. Chheda with UF Health.

What to Expect from the Procedure

There are two methods of using Botox to induce burping, according to Robert Bastian, MD, an otolaryngologist (ear, nose and throat doctor) and director of Bastian Voice Institute in Downers Grove, Illinois.

Procedure Options

  • Brief procedure under general anesthesia in an outpatient operating room
  • Injection into the muscle while the patient is sitting in a chair in a doctor’s office

The Results

A patient of Dr. Bastian spoke about the effectiveness of the procedure, saying it has allowed them to burp, that "any gurgling is gone," and that "bloating has diminished almost entirely." The patient also noted that getting the procedure has "drastically" improved their day-to-day life.

Conclusion

For those affected by no burp syndrome, Botox may offer a potential solution. With two procedure options available, patients can choose the method that best suits their needs. As Dr. Bastian said, it has been a great privilege to pioneer the Botox method, and he is honored to work with patients who have suffered from this terrible disorder.

Frequently Asked Questions

Q: Is Botox safe?
A: Yes, as long as it is injected into the correct and intended muscle.

Q: How effective is Botox for no burp syndrome?
A: Botox can help alleviate symptoms and improve quality of life.

Q: How long does the effect of Botox last?
A: The effect of Botox can last for several months, depending on individual factors.

Q: Are there any side effects to Botox?
A: As with any medication, there may be side effects, but these are typically mild and temporary.

Q: Who can get Botox?
A: Both men and women can get Botox, and it is recommended that individuals consult a qualified medical professional to determine the best course of treatment.

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