The Quest for a Hangover Cure: Do Probiotics Really Work?
A Promising Solution or a False Hope?
The ads on podcasts and social media promised a solution to the woes of the morning after: over-the-counter probiotic supplements that could ward off the worst effects of a hangover if taken before drinking. Eric Burke, a bourbon reviewer, was intrigued and decided to test out Pre-Alcohol, a probiotic drink from ZBiotics.
A Mixed Bag of Results
Burke downed the mixture of water, salt, flavoring, and genetically modified bacteria before consuming a cocktail, a meal, and two bourbons. The next morning, he woke up feeling "considerably more chipper than he’d have expected." However, his second attempt was a different story. Despite taking another half-ounce bottle of Pre-Alcohol, he woke up feeling "just like, ‘Well, I’m not 21 anymore.’"
How Probiotics Work (or Don’t)
Probiotics, like those in Pre-Alcohol and Myrkl, rely on live bacteria to process excess acetaldehyde, a chemical byproduct of alcohol breakdown in the body. The hypothesis is that reducing acetaldehyde levels will also reduce physical symptoms. However, researchers warn that the bloodstream carries most of the ethanol to the liver, where it’s broken down into acetaldehyde, making it unlikely that probiotics alone can make a significant impact.
The Science Behind Probiotics and Hangovers
Karsten Zengler, a microbiologist and professor of pediatrics and bioengineering at UC San Diego, explained that the intestines come pre-equipped with an army of bacteria capable of breaking down alcohol’s byproducts. Adding probiotics might not have a substantial effect on how you feel the next day.
Real-World Effects
ZBiotics has funded studies demonstrating the safety and effectiveness of their product in simulated gut conditions. However, the real-world effects of their supplement are unclear. Myrkl’s study showed that its product lowered blood-alcohol levels in some participants, but the subjects were instructed to take the supplement for a week prior to drinking, not as a single pre-party dose.
The Verdict
Joris C. Verster, a pharmacology professor at Utrecht University, concluded that there is currently one scientifically validated way to prevent hangovers: drink less alcohol. "Although there are many hangover products marketed, there is no convincing scientific evidence that these treatments are effective."
Conclusion
While probiotics may offer some benefits, the science is unclear, and more research is needed to determine their effectiveness. For now, the best way to prevent hangovers is to consume alcohol in moderation.
Frequently Asked Questions
Q: Can probiotics really prevent hangovers?
A: The scientific consensus is that probiotics alone are unlikely to make a significant impact on hangover symptoms.
Q: Are there any scientifically validated ways to prevent hangovers?
A: Yes, the only scientifically validated way to prevent hangovers is to consume alcohol in moderation.
Q: What is the best way to prevent hangovers?
A: The best way to prevent hangovers is to drink less alcohol.
