Friday, October 3, 2025

Do Covid Vaccines Provide Long-Lasting Protection?

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CDC Recommends Second Dose of Covid Vaccine for High-Risk Groups

The Centers for Disease Control and Prevention (CDC) has recommended that high-risk adults get a second updated Covid vaccine to bolster their protection against the virus. The agency now recommends that people ages 65 and up and those with weakened immune systems get a second dose of the 2024-25 vaccine six months after their first dose.

Why the New Recommendation?

The CDC’s decision is based on a recent study from researchers at Emory University, which found that so-called hybrid immunity – when a person has been both vaccinated and infected with the coronavirus – failed to significantly establish certain long-lasting cells that secrete antibodies. This suggests that something unique is happening with the virus that prevents people’s bodies from maintaining high levels of immunity.

Is the mRNA Vaccine Effective?

Despite the CDC’s recommendation for an additional shot, there is no evidence that the mRNA vaccines are not working as expected, said Akiko Iwasaki, a professor of immunology at the Yale School of Medicine. However, she noted that there may be something unique to this virus that is preventing people’s bodies from maintaining high levels of immunity.

The Impact of Waning Immunity

The new guidance comes amid concerns that waning vaccine immunity, particularly in older adults, may leave them more vulnerable to severe disease and hospitalization. "Topping off your vaccine-induced immunity every six to 12 months is not a bad idea," said E. John Wherry, an immunologist at the University of Pennsylvania.

The Rapidly Changing Virus

The coronavirus is constantly mutating, making it challenging to keep up with the latest strains. "It’s changing even faster with Covid – it’s constantly mutating to get the advantage," said Dr. Anna Durbin, an infectious disease physician and associate professor at the Johns Hopkins University School of Medicine.

Conclusion

The new guidance is an effort to boost immunity in high-risk groups, particularly those 65 and older, and those with weakened immune systems. The CDC’s recommendation is based on the understanding that the virus is constantly mutating, and booster shots can help keep pace with these changes.

FAQs

Q: Why is the CDC recommending a second dose of the Covid vaccine?
A: The CDC is recommending a second dose to boost immunity in high-risk groups, particularly those 65 and older, and those with weakened immune systems, to prevent severe disease and hospitalization.

Q: Is the mRNA vaccine effective?
A: Yes, the mRNA vaccines have been shown to be effective in inducing immunity, but there may be something unique to this virus that prevents people’s bodies from maintaining high levels of immunity.

Q: Why do we need to keep up with the latest strains of the virus?
A: The coronavirus is constantly mutating, making it challenging to keep up with the latest strains. Booster shots can help keep pace with these changes and provide better protection against the virus.

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