Introduction to Vaccine Development Funding Cuts
WASHINGTON — The Department of Health and Human Services will cancel contracts and pull funding for some vaccines that are being developed to fight respiratory viruses like COVID-19 and the flu.
Background on the Decision
Robert F. Kennedy Jr. announced in a statement Tuesday that 22 projects, totaling $500 million, to develop vaccines using mRNA technology will be halted. Kennedy’s decision to terminate the projects is the latest in a string of decisions that have put the longtime vaccine critic’s doubts about shots into full effect at the nation’s health department. Kennedy has pulled back recommendations around the COVID-19 shots, fired the panel that makes vaccine recommendations, and refused to offer a vigorous endorsement of vaccinations as a measles outbreak worsened.
Reasons Behind the Decision
The health secretary criticized mRNA vaccines in a video on his social media accounts, explaining the decision to cancel projects being led by the nation’s leading pharmaceutical companies, including Pfizer and Moderna, that offer protection against viruses like the flu, COVID-19 and H5N1. “To replace the troubled mRNA programs, we’re prioritizing the development of safer, broader vaccine strategies, like whole-virus vaccines and novel platforms that don’t collapse when viruses mutate,” Kennedy said in the video.
Expert Reactions
Infectious disease experts say the mRNA technology used in vaccines is safe, and they credit its development during the first Trump administration with slowing the 2020 coronavirus pandemic. Future pandemics, they warned, will be harder to stop without the help of mRNA. “I don’t think I’ve seen a more dangerous decision in public health in my 50 years in the business,” said Mike Osterholm, a University of Minnesota expert on infectious diseases and pandemic preparations. He noted mRNA technology offers potential advantages of rapid production, crucial in the event of a new pandemic that requires a new vaccine.
Impact on Pandemic Preparations
The shelving of the mRNA projects is short-sighted as concerns about a bird flu pandemic continue to loom, said Dr. Paul Offit, a vaccine expert at Children’s Hospital of Philadelphia. “It’s certainly saved millions of lives,” Offit said of the existing mRNA vaccines. Scientists are using mRNA for more than infectious disease vaccines, with researchers around the world exploring its use for cancer immunotherapies. At the White House earlier this year, billionaire tech entrepreneur Larry Ellison praised mRNA for its potential to treat cancer.
How mRNA Technology Works
Traditionally, vaccines have required growing pieces of viruses, often in chicken eggs or giant vats of cells, then purifying that material. The mRNA approach starts with a snippet of genetic code that carries instructions for making proteins. Scientists pick the protein to target, inject that blueprint and the body makes just enough to trigger immune protection — producing its own vaccine dose.
Future of Vaccine Development
In a statement Tuesday, HHS said “other uses of mRNA technology within the department are not impacted by this announcement.” The mRNA technology is used in approved COVID-19 and RSV shots, but has not yet been approved for a flu shot. Moderna, which was studying a combination COVID-19 and flu mRNA shot, had said it believed mRNA could speed up production of flu shots compared with traditional vaccines. The abandoned mRNA projects signal a “shift in vaccine development priorities,” the health department said in its statement, adding that it will start “investing in better solutions.” “Let me be absolutely clear, HHS supports safe, effective vaccines for every American who wants them,” Kennedy said in the statement.
Alternative Vaccine Development
Speaking hours later Tuesday at a news conference in Anchorage, Alaska, alongside the state’s two Republican U.S. senators, Kennedy said work is underway on an alternative. He said a “universal vaccine” that mimics “natural immunity” is the administration’s focus. “It could be effective — we believe it’s going to be effective — against not only coronaviruses, but also flu,” he said.
Conclusion
The decision to pull $500 million in funding for mRNA vaccine development has sparked controversy and concern among infectious disease experts. While the administration believes that safer, broader vaccine strategies are needed, experts warn that abandoning mRNA technology could hinder pandemic preparations and put lives at risk. As the nation’s health department shifts its priorities, it remains to be seen how this decision will impact the development of vaccines and the fight against respiratory viruses.
FAQs
Q: What is mRNA technology and how is it used in vaccines?
A: mRNA technology uses a snippet of genetic code to carry instructions for making proteins, which triggers immune protection and produces a vaccine dose.
Q: Why did Robert F. Kennedy Jr. decide to pull funding for mRNA vaccine development?
A: Kennedy criticized mRNA vaccines, citing concerns about their safety and effectiveness, and announced that the department will prioritize safer, broader vaccine strategies.
Q: What are the potential consequences of abandoning mRNA technology?
A: Experts warn that abandoning mRNA technology could hinder pandemic preparations, put lives at risk, and make it harder to stop future pandemics.
Q: What alternative vaccine development is the administration focusing on?
A: The administration is working on a “universal vaccine” that mimics “natural immunity” and could be effective against coronaviruses and flu.
