Sunday, October 19, 2025

Acting CDC director calls to ‘break up’ MMR vaccine into 3 shots – NBC Chicago

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Introduction to the MMR Vaccine Debate

Acting CDC Director Jim O’Neill on Monday called on vaccine manufacturers to develop separate shots for measles, mumps and rubella instead of the current vaccine, which combines the three.

O’Neill wrote in a post on X that manufacturers should replace the MMR vaccine with “safe monovalent vaccines,” which only target one virus. His statement referenced a recent comment from President Donald Trump, who advised people last month on Truth Social to “break up the MMR shot into three totally separate shots.”

Background on the MMR Vaccine

The measles, mumps and rubella vaccine has been available as a combination shot since 1971, in part to reduce the number of injections that children receive, given that the three are administered at the same ages. However, no monovalent vaccines for measles, mumps or rubella are approved in the U.S., and the Centers for Disease Control and Prevention says there is no published scientific evidence that shows a benefit to separating the combined vaccine.

Potential Consequences of Breaking Up the MMR Vaccine

Breaking up the MMR vaccine, a two-dose regimen in which the first shot is recommended at 12 to 15 months and the second at 4 to 6 years, would mean that children would receive six injections instead of two. It’s unclear where Trump’s advice came from, as the White House is not responsible for setting vaccine or drug use recommendations.

Statements from President Trump and Health Secretary

At a White House event on Sept. 22, the president expressed a preference for individual over combined shots while at the same time decrying the number of vaccines that kids receive, saying that “too many different things are going into that baby at too big a number.” “The MMR, I think, should be taken separately,” Trump said. “This is based on what I feel. … It seems to be that when you mix them, there could be a problem. So there’s no downside in taking them separately.” Health Secretary Robert F. Kennedy Jr., who in the past founded an anti-vaccine group, has repeatedly made false claims about measles vaccines, including that they haven’t been “safety tested” and that their protection is short-lived.

Response from Merck and the CDC

Merck, the pharmaceutical company that has manufactured the MMR vaccine since 1971, said in a statement that use of individual vaccines “increases the number of injections for the individual and may result in delayed or missed immunizations.” At the same time, the company added, “evidence suggests that use of combination vaccines improves childhood vaccination outcomes, increasing both completion (receipt of all recommended doses) and compliance (age-appropriate administration) rates.” The U.S. has recorded more measles cases this year than in any other since 2000, when the country eliminated the disease.

Recent Developments and Recommendations

The Department of Health and Human Services has already moved to limit access to a combination MMR and chickenpox vaccine for children. The CDC’s vaccine advisory committee recommended on Sept. 18 against that vaccine for children under 4. O’Neill, who is also the deputy health secretary, signed off on the recommendation last week. The committee’s recommendation was based on an increased risk of febrile seizures (seizures prompted by fevers that tend to resolve quickly), which doctors had known about for years.

Conclusion

The debate over the MMR vaccine has sparked a significant discussion about the effectiveness and safety of combination vaccines. While some argue that breaking up the MMR vaccine into separate shots could reduce potential risks, others point to the lack of scientific evidence supporting this approach. As the situation continues to unfold, it is essential to consider the potential consequences of such a change and to prioritize evidence-based decision-making in the realm of public health.

FAQs

  1. What is the current recommendation for the MMR vaccine?
    The current recommendation is to administer the MMR vaccine as a combination shot, with the first dose given at 12 to 15 months and the second dose at 4 to 6 years.
  2. What are the potential consequences of breaking up the MMR vaccine into separate shots?
    Breaking up the MMR vaccine could result in children receiving six injections instead of two, potentially leading to delayed or missed immunizations.
  3. What does the scientific evidence say about the effectiveness of combination vaccines?
    The scientific evidence suggests that combination vaccines, like the MMR vaccine, improve childhood vaccination outcomes by increasing completion and compliance rates.
  4. What is the response from Merck, the manufacturer of the MMR vaccine?
    Merck states that use of individual vaccines increases the number of injections and may result in delayed or missed immunizations, while also acknowledging that combination vaccines improve childhood vaccination outcomes.
  5. What is the current situation with measles cases in the U.S.?
    The U.S. has recorded more measles cases this year than in any other since 2000, when the country eliminated the disease.
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